NC State
Robert Smart Lab

We have active projects on: 1) the role of long noncoding RNAs lincRNAp21 aka Trp53Cor1 and Soal in regulating the cellular decision to live or die in response to DNA damage and 2) the role of Nrf2 in development and progression of cutaneous squamous cell carcinoma (cSCC).

Current basic skin biology projects include investigating the role of C/EBPβ in the regulation of the synthesis of epidermal lipids and skin barrier function – we are conducting  muti-omic analyses (lipidomics and transcriptomics)  of epidermis of wildtype mice and mice lacking C/EBPβ in their epidermis.